Dr. Lawrence Appel is Director of the Welch Center for Prevention, Epidemiology and Clinical Research, a joint program of the Johns Hopkins School of Medicine and the Bloomberg School of Public Health. Dr. Appel is a Professor of Medicine with adjunct appointments in Epidemiology and International Health. The focus of Dr. Appel’s investigative career is the conduct of clinical, epidemiologic and translational research pertaining to the prevention of hypertension, cardiovascular disease, and kidney disease.
Currently, he has three large, successful, and complementary research programs:
large-scale feeding trials that identify optimal diet
behavioral intervention trials that test novel strategies to accomplish lifestyle modification, often focused on obesity
trials and observational studies to understand risk factors for chronic kidney disease progression and its complications
Many of Dr. Appel’s completed studies are considered landmark efforts (e.g. DASH, PREMIER, AASK) that have influenced health care policy. A particularly notable feature of this research is the focus on conditions and diseases that disproportionately afflict minorities and on interventions that have the potential to substantially reduce racial disparities.
Dr. Appel has been actively involved in health care policy. He was a member of the 2005 and 2010 U.S. Dietary Guidelines Scientific Advisory Committees. For the American Heart Association, he has been a member of its Nutrition Committee for over 10 years and a past chair. He has also served on several Institute of Medicine Committees and chaired the committee that set dietary reference intakes for sodium, potassium and water. He has served on numerous advisory committees for the National Institutes of Health.